This latch is made for Emtek knob or leversets for doors that have drive in latch prep (no rectangular mortise faceplate on the edge of the door) and a standard 2 1/8" bore hole. As far as compatability with antique knob & spindle hardware, its hard to say, you could try it but understand it may or may not work and we don't represent it to fit anything other than Emtek locksets.
We carry a manufacturer called Nostalgic Warehouse that makes a lot of antique looking and replacement hardware. See:
https://www.directdoorhardware.com/Nostalgic_Warehouse.htm
Answer provided by: Zach (11/1/2018)